Ce facem

Concepem si realizam experimente stiintifice in laborator cu scopul de a descoperi metode noi de tratament pentru boli ce afecteaza o mare parte din populatie, precum:

Imbatranirea populatiei din intreaga Uniune Europeana este un fapt. Este esential ca in anii urmatori sa se descopere metode de a prelungi viata activa a oamenilor si de a imbunatati sanatatea celor cu varsta inaintata concomitent cu scaderea costurilor pentru sistemele de asigurari de sanatate.

La prima vedere par lucruri greu de realizat. Noi credem ca niciun efort in aceste directii nu este zadarnic si activitatea noastra ghidata de pasiune si curiozitate poate aduce intregii societati un beneficiu important.

Publicatii

• Popescu, R. G., Marinescu, G. C., Rădulescu, A. L., Marin, D. E., Țăranu, I., & Dinischiotu, A. (2023). Natural Antioxidant By-Product Mixture Counteracts the Effects of Aflatoxin B1 and Ochratoxin A Exposure of Piglets after Weaning: A Proteomic Survey on Liver Microsomal Fraction. Toxins, 15(4), 299. https://doi.org/10.3390/toxins15040299

• Popescu, R. G., Dinischiotu, A., Soare, T., Vlase, E., Marinescu, G. C. (2023). NMN Works in HFD-Induced T2DM by Interesting Effects in Adipose Tissue, and Not by Mitochondrial Biogenesis. bioRxiv, 2023.10.27.564318. https://doi.org/10.1101/2023.10.27.564318

• Marinescu G. C., Popescu R.G., Dinischiotu A. (2018). Nicotinamide mononucleotide (NMN) effects on mitochondrial OXPHOS protein expression. 12th Central and Eastern European Proteomic Conference October 24 – 26, 2018, Institute of Cellular Biology and Pathology "Nicolae Simionescu", Bucharest, Romania.

• Proteomics Identification Database Proteomics dataset, deposited in Proteomics Identification Database (https://www.ebi.ac.uk/pride): PXD043257 SWATH proteomics of NMN effects; PXD040040 SWATH proteomics analysis of pig liver microsomes.

• Plasmids #83362, #83363, #91950 developed for NMN production deposited to be shared with research community at Addgene https://www.addgene.org/George_Catalin_Marinescu

• Marinescu G.C., Popescu R.-G., Stoian G., Dinischiotu A. (2018). β-nicotinamide mononucleotide (NMN) production in Escherichia coli. Nature Scientific Reports, vol 8, 12278. doi:10.1038/s41598-018-30792-0. https://www.nature.com/articles/s41598-018-30792-0

• Marinescu G.C., Popescu R.-G., Dinischiotu A. (2018). Size Exclusion Chromatography Method for Purification of Nicotinamide Mononucleotide (NMN) from Bacterial Cells. Nature Scientific Reports, vol 8, 4433. doi:10.1038/s41598-018-22806-8. https://www.nature.com/articles/s41598-018-22806-8

• Marinescu G.C., Popescu R.G. (2018). Open-Source bioreactor controller for bacterial protein expression. PeerJ Preprints 6:e27150v1. https://doi.org/10.7287/peerj.preprints.27150v1